|
Glaucoma, Primary Open Angle
|
|
0.020 |
GeneticVariation
|
BEFREE |
Among women with age at menarche <13 years, compared with the CC homozygotes of the rs3918188 tagging SNP, the wild-type AA homozygotes were at significantly reduced risk of POAG (RR=0.31, 95% CI=0.16, 0.59); however, for women with age at menarche ≥13 years, the SNP was not associated with POAG (p-interaction=0.0007).
|
22025889 |
2011 |
|
Glaucoma, Primary Open Angle
|
|
0.020 |
GeneticVariation
|
BEFREE |
rs3793342, rs743507, rs11771443, rs7830, and rs3918188 were not found to be associated with POAG or with PCAG.
|
21245953 |
2011 |
|
Essential Hypertension
|
|
0.010 |
GeneticVariation
|
BEFREE |
We examined whether the NOS3 tagSNPs rs3918226, rs3918188, and rs743506, and their haplotypes, affect the antihypertensive responses to enalapril in 101 patients with essential hypertension.
|
27060232 |
2016 |
|
Diabetes
|
|
0.010 |
GeneticVariation
|
BEFREE |
These preliminary findings indicate that the NOS2 rs2779248, NOS2 rs1137933, and NOS3 rs3918188 genetic polymorphisms are potentially related to the susceptibility to T2DM, and the rs1800783 polymorphism might be considered as genetic risk factors for diabetic nephropathy, and family history of diabetes was closely associated with rs11771443 polymorphism in DN, and the genetic variants might be used as molecular markers for evaluating the risk of T2DM and diabetic nephropathy.© 2016 IUBMB Life, 68(7):516-525, 2016.
|
27192959 |
2016 |
|
Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
These preliminary findings indicate that the NOS2 rs2779248, NOS2 rs1137933, and NOS3 rs3918188 genetic polymorphisms are potentially related to the susceptibility to T2DM, and the rs1800783 polymorphism might be considered as genetic risk factors for diabetic nephropathy, and family history of diabetes was closely associated with rs11771443 polymorphism in DN, and the genetic variants might be used as molecular markers for evaluating the risk of T2DM and diabetic nephropathy.© 2016 IUBMB Life, 68(7):516-525, 2016.
|
27192959 |
2016 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.010 |
GeneticVariation
|
BEFREE |
These preliminary findings indicate that the NOS2 rs2779248, NOS2 rs1137933, and NOS3 rs3918188 genetic polymorphisms are potentially related to the susceptibility to T2DM, and the rs1800783 polymorphism might be considered as genetic risk factors for diabetic nephropathy, and family history of diabetes was closely associated with rs11771443 polymorphism in DN, and the genetic variants might be used as molecular markers for evaluating the risk of T2DM and diabetic nephropathy.© 2016 IUBMB Life, 68(7):516-525, 2016.
|
27192959 |
2016 |
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
To determine if the NOS3 genetic variants are associated with CAD in the Han Chinese, we examined the potential association between CAD and eight single nucleotide polymorphisms (rs1799983, rs2070744, rs11771443, rs3918188, rs2853796, rs7830, rs1541861, and rs2853792) of the NOS3 using the MassARRAY system.
|
27323132 |
2016 |
|
Diabetic Nephropathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
These preliminary findings indicate that the NOS2 rs2779248, NOS2 rs1137933, and NOS3 rs3918188 genetic polymorphisms are potentially related to the susceptibility to T2DM, and the rs1800783 polymorphism might be considered as genetic risk factors for diabetic nephropathy, and family history of diabetes was closely associated with rs11771443 polymorphism in DN, and the genetic variants might be used as molecular markers for evaluating the risk of T2DM and diabetic nephropathy.© 2016 IUBMB Life, 68(7):516-525, 2016.
|
27192959 |
2016 |
|
Pediatric Obesity
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, no study has tested the hypothesis that NOS3 tagSNPs rs3918226, rs3918188, rs743506 and rs7830 affect nitrite levels and are associated with hypertension in childhood obesity.
|
24943287 |
2015 |
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, no study has tested the hypothesis that NOS3 tagSNPs rs3918226, rs3918188, rs743506 and rs7830 affect nitrite levels and are associated with hypertension in childhood obesity.
|
24943287 |
2015 |
|
Intraocular pressure disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
There were 102 POAG and 88 PCAG patients, diagnosed on the basis of clinical history, raised intraocular pressure (IOP), cup-to-disc ratio (CDR) and visual field defects, and 120 age- and sex-matched control subjects genotyped for 5 tagging single nucleotide polymorphisms (SNPs; rs743507, rs3793342, rs11771443, rs7830, and rs3918188) of the human eNOS gene.
|
21245953 |
2011 |