|
AUTISM, SUSCEPTIBILITY TO, 15
|
|
0.700 |
SusceptibilityMutation
|
CLINVAR |
|
|
|
|
Autism Spectrum Disorders
|
|
0.040 |
GeneticVariation
|
BEFREE |
In the updated meta-analysis, the association between the two frequently reported SNPs (rs2710102 and rs7794745) in CNTNAP2 and the risk of ASD was explored.
|
30681286 |
2019 |
|
Autistic Disorder
|
|
0.040 |
GeneticVariation
|
BEFREE |
The results of this study showed that there is a significant association between rs7794745 CNTNAP2 gene polymorphism and autism in the studied population.
|
28284582 |
2017 |
|
Autism Spectrum Disorders
|
|
0.040 |
GeneticVariation
|
BEFREE |
The results revealed higher frequency distributions statistically significant (P = 0.034) of the homozygous SNP rs7794745 (presumed risk genotype) in ASD patients as compared with control subjects.
|
26909962 |
2016 |
|
Autistic Disorder
|
|
0.040 |
GeneticVariation
|
BEFREE |
One of the most striking interspecies differences with 28% methylation in human and 59% in chimpanzee cortex (by bisulfite pyrosequencing) lies in a region 300 bp upstream of human SNP rs7794745 which has been associated with autism and parent-of-origin effects.
|
24434791 |
2014 |
|
Autistic Disorder
|
|
0.040 |
GeneticVariation
|
BEFREE |
Furthermore, we failed to replicate in our sample a previous association finding of two single nucleotide polymorphisms (rs2710102 and rs7794745) in the CNTNAP2 gene with autism.
|
23277129 |
2013 |
|
Autism Spectrum Disorders
|
|
0.040 |
GeneticVariation
|
BEFREE |
Five single nucleotide polymorphisms in CNTNAP2 (including rs7794745 and rs2710102, previously associated with ASDs) were genotyped.
|
21193173 |
2011 |
|
Autistic Disorder
|
|
0.040 |
GeneticVariation
|
BEFREE |
In the current study we investigated the functional effects of variants of CNTNAP2 associated with autism and language impairment (rs7794745 and rs2710102; presumed risk alleles T and C, respectively) in healthy individuals using functional magnetic resonance imaging (fMRI) during performance of a language task (n = 66).
|
21987501 |
2011 |
|
Autism Spectrum Disorders
|
|
0.040 |
GeneticVariation
|
BEFREE |
A total of 110 adult patients with ASD (n=61) or ADHD (n=49) with or without a lifetime history of SUD participated in a study in which we genotyped polymorphisms in five known candidate genes for (one of) the disorders, i.e. the 5HTTLPR in SLC6A4/5-HTT, rs1800497 (TaqIA C>T) in DRD2, rs7794745 in CNTNAP2, rs1843809 in TPH2, and rs6565113 in CDH13.
|
20446882 |
2010 |
|
Language Disorders
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the current study we investigated the functional effects of variants of CNTNAP2 associated with autism and language impairment (rs7794745 and rs2710102; presumed risk alleles T and C, respectively) in healthy individuals using functional magnetic resonance imaging (fMRI) during performance of a language task (n = 66).
|
21987501 |
2011 |
|
Substance Use Disorders
|
|
0.010 |
GeneticVariation
|
BEFREE |
A total of 110 adult patients with ASD (n=61) or ADHD (n=49) with or without a lifetime history of SUD participated in a study in which we genotyped polymorphisms in five known candidate genes for (one of) the disorders, i.e. the 5HTTLPR in SLC6A4/5-HTT, rs1800497 (TaqIA C>T) in DRD2, rs7794745 in CNTNAP2, rs1843809 in TPH2, and rs6565113 in CDH13.
|
20446882 |
2010 |
|
Attention deficit hyperactivity disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
A total of 110 adult patients with ASD (n=61) or ADHD (n=49) with or without a lifetime history of SUD participated in a study in which we genotyped polymorphisms in five known candidate genes for (one of) the disorders, i.e. the 5HTTLPR in SLC6A4/5-HTT, rs1800497 (TaqIA C>T) in DRD2, rs7794745 in CNTNAP2, rs1843809 in TPH2, and rs6565113 in CDH13.
|
20446882 |
2010 |