Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 101
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 41
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885 12
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 26
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 23
SLC17A8 Q8NDX2 solute carrier family 17 member 8 Transporter 1.3E-03 0.729 0.462 8
SLC17A7 Q9P2U7 solute carrier family 17 member 7 Transporter 1.00 0.636 0.308 2
SCN10A Q9Y5Y9 sodium voltage-gated channel alpha subunit 10 Ion channel 9.9E-38 0.566 0.692 2
SNW1 Q13573 SNW domain containing 1 Transcription factor 1.00 0.682 0.423 1
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
RCHY1 Q96PM5 ring finger and CHY zinc finger domain containing 1 Enzyme 6.6E-02 0.716 0.462 1
RPSA P08865 ribosomal protein SA Nucleic acid binding 0.93 0.485 0.769 5
RGMA Q96B86 repulsive guidance molecule BMP co-receptor a 0.16 0.656 0.692 3
REG3A Q06141 regenerating family member 3 alpha 6.3E-04 0.522 0.769 6
RAN P62826 RAN, member RAS oncogene family Enzyme modulator 0.98 0.576 0.808 1
RANGAP1 P46060 Ran GTPase activating protein 1 Enzyme modulator 2.6E-02 0.617 0.538 1
RANBP1 P43487 RAN binding protein 1 Enzyme modulator 0.82 0.736 0.615 2
PCSK5 Q92824 proprotein convertase subtilisin/kexin type 5 Enzyme 2.5E-12 0.659 0.538 10
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846 17
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885 42
KCNC4 Q03721 potassium voltage-gated channel subfamily C member 4 Ion channel 4.5E-03 0.722 0.423 3
KCNJ8 Q15842 potassium inwardly rectifying channel subfamily J member 8 Ion channel 0.38 0.619 0.538 9
KCNJ11 Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 1.1E-02 0.529 0.615 12
PTN P21246 pleiotrophin Signaling 7.5E-03 0.515 0.808 9