Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846 18
ABCC9 O60706 ATP binding cassette subfamily C member 9 Transporter 9.4E-09 0.552 0.692 10
SLC17A8 Q8NDX2 solute carrier family 17 member 8 Transporter 1.3E-03 0.729 0.462 8
LAMP2 P13473 lysosomal associated membrane protein 2 Transporter 0.27 0.552 0.731 8
SLC17A7 Q9P2U7 solute carrier family 17 member 7 Transporter 1.00 0.636 0.308 2
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885 42
SNW1 Q13573 SNW domain containing 1 Transcription factor 1.00 0.682 0.423 1
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 101
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 94
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 20
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 17
PTN P21246 pleiotrophin Signaling 7.5E-03 0.515 0.808 9
NRG1 Q02297 neuregulin 1 Signaling 1.00 0.464 0.885 8
NOS1AP O75052 nitric oxide synthase 1 adaptor protein Signaling 0.61 0.608 0.423 5
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885 3
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846 23
MAG P20916 myelin associated glycoprotein Receptor 0.49 0.579 0.692 5
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 23
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846 17
RPSA P08865 ribosomal protein SA Nucleic acid binding 0.93 0.485 0.769 5
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 26