Source: GWASDB

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 4 4
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 1 4
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 30 202
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 6 3
IL33 O95760 interleukin 33 8.3E-10 0.409 0.885 3 10
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 7 16
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846 23 65
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 3 20
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 13 4
KLK3 P07288 kallikrein related peptidase 3 Enzyme 4.4E-06 0.443 0.885 3 3
ETS1 P14921 ETS proto-oncogene 1, transcription factor Transcription factor 0.78 0.444 0.731 7 4
CDK2 P24941 cyclin dependent kinase 2 Kinase 0.61 0.456 0.692 2 1
MST1 P26927 macrophage stimulating 1 Enzyme 4.8E-19 0.465 0.885 6 1
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769 11 20
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 11 11
IL18R1 Q13478 interleukin 18 receptor 1 Receptor 8.6E-06 0.473 0.808 7 59
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 32 28
IL2RB P14784 interleukin 2 receptor subunit beta Receptor 0.29 0.491 0.846 10 6
ICOS Q9Y6W8 inducible T cell costimulator 3.1E-02 0.502 0.731 5 1
PROC P04070 protein C, inactivator of coagulation factors Va and VIIIa Enzyme 1.9E-05 0.504 0.808 3 6
ITGAX P20702 integrin subunit alpha X 1.4E-15 0.504 0.769 2 3
CCHCR1 Q8TD31 coiled-coil alpha-helical rod protein 1 1.0E-16 0.505 0.808 13 13
IL1R1 P14778 interleukin 1 receptor type 1 Receptor 0.15 0.509 0.769 6 16
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808 4 6