Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
HLA-DRB3 P79483 major histocompatibility complex, class II, DR beta 3 Immune response 0.570 0.885 6
IBD5 inflammatory bowel disease 5 0.705 0.538 4
MST1R Q04912 macrophage stimulating 1 receptor Kinase 7.9E-37 0.542 0.808 13
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 25
VIPR1 P32241 vasoactive intestinal peptide receptor 1 G-protein coupled receptor 7.4E-27 0.573 0.654 8
IRAK3 Q9Y616 interleukin 1 receptor associated kinase 3 Kinase 5.3E-21 0.615 0.615 3
MST1 P26927 macrophage stimulating 1 Enzyme 4.8E-19 0.465 0.885 3
ALPI P09923 alkaline phosphatase, intestinal Enzyme 2.5E-18 0.563 0.769 2
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 48
PADI4 Q9UM07 peptidyl arginine deiminase 4 4.6E-16 0.494 0.808 6
APOH P02749 apolipoprotein H 1.6E-15 0.563 0.769 14
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 67
ECM1 Q16610 extracellular matrix protein 1 4.7E-14 0.576 0.731 1
CD209 Q9NNX6 CD209 molecule Receptor 2.7E-13 0.626 0.769 12
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 18
KRT7 P08729 keratin 7 3.1E-12 0.463 0.808 13
CD55 P08174 CD55 molecule (Cromer blood group) 5.7E-12 0.510 0.808 12
HLA-G P17693 major histocompatibility complex, class I, G 1.4E-11 0.461 0.769 46
BTNL2 Q9UIR0 butyrophilin like 2 Enzyme modulator 8.6E-11 0.546 0.808 9
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846 17
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 52
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 110
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885 36
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808 28