Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL6 P05231 interleukin 6 0.32 0.248 0.962 177
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 134
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 112
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 110
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 95
IFNG P01579 interferon gamma 0.47 0.288 0.962 91
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 89
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 85
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 84
LEP P41159 leptin 0.46 0.349 0.846 78
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 67
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 67
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 55
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 53
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 53
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 52
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 50
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 49
HLA-G P17693 major histocompatibility complex, class I, G 1.4E-11 0.461 0.769 46
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885 43
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846 36
CD40 P25942 CD40 molecule 0.85 0.396 0.846 36
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 31
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885 29