Source: GWASDB

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 7 9
SLCO6A1 Q86UG4 solute carrier organic anion transporter family member 6A1 Transporter 2.9E-11 0.412 0.885 1 1
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 2 2
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846 23 65
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 1 1
PRKAA1 Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 0.14 0.453 0.846 2 3
NRG1 Q02297 neuregulin 1 Signaling 1.00 0.464 0.885 8 8
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846 3 6
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808 2 6
CDH13 P55290 cadherin 13 7.1E-04 0.501 0.846 4 10
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846 12 32
AKT3 Q9Y243 AKT serine/threonine kinase 3 Kinase 1.00 0.512 0.808 5 3
RELN P78509 reelin 1.00 0.515 0.731 2 2
HK2 P52789 hexokinase 2 Kinase 4.6E-03 0.515 0.769 1 1
PDE4D Q08499 phosphodiesterase 4D 1.00 0.519 0.846 9 12
NTRK3 Q16288 neurotrophic receptor tyrosine kinase 3 Kinase 1.00 0.522 0.692 1 1
NFATC2 Q13469 nuclear factor of activated T cells 2 Transcription factor 1.00 0.525 0.731 2 9
RENBP P51606 renin binding protein Enzyme 0.45 0.528 0.769 1 1
DLC1 Q96QB1 DLC1 Rho GTPase activating protein 1.00 0.529 0.731 2 2
RORA P35398 RAR related orphan receptor A Nuclear receptor 0.40 0.533 0.808 8 10
NOTCH4 Q99466 notch receptor 4 2.1E-23 0.534 0.731 24 38
ATXN1 P54253 ataxin 1 0.97 0.534 0.769 1 1
NT5C2 P49902 5'-nucleotidase, cytosolic II Enzyme 2.1E-06 0.537 0.846 5 2
SCN4A P35499 sodium voltage-gated channel alpha subunit 4 Ion channel 1.3E-02 0.554 0.731 1 1