Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CD24 P25063 CD24 molecule 0.472 0.769 20
IGH immunoglobulin heavy locus 0.473 0.654 9
HLA-DRB4 P13762 major histocompatibility complex, class II, DR beta 4 Immune response 0.565 0.846 7
BLACE A4D250 B cell acute lymphoblastic leukemia expressed 0.931 0.115 1
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 32
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885 20
RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 Enzyme modulator 7.1E-23 0.593 0.692 1
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808 27
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846 40
TTC12 Q9H892 tetratricopeptide repeat domain 12 1.8E-17 0.780 0.192 1
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 149
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808 17
COL18A1 P39060 collagen type XVIII alpha 1 chain 1.7E-10 0.449 0.808 19
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 110
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923 9
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 21
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 25
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846 40
F13A1 P00488 coagulation factor XIII A chain Enzyme 5.3E-08 0.575 0.731 14
ITPA Q9BY32 inosine triphosphatase Enzyme 1.0E-07 0.604 0.500 3
BIRC7 Q96CA5 baculoviral IAP repeat containing 7 Enzyme modulator 1.1E-07 0.621 0.500 9
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846 14
PRAME P78395 preferentially expressed antigen in melanoma 2.4E-07 0.531 0.577 8
ZNHIT3 Q15649 zinc finger HIT-type containing 3 5.5E-07 0.666 0.462 1