Source: HPO

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 43
ACTA1 P68133 actin alpha 1, skeletal muscle Cellular structure 1.1E-06 0.540 0.769 147
ALG12 Q9BV10 ALG12 alpha-1,6-mannosyltransferase Enzyme 1.2E-07 0.705 0.500 43
APC2 O95996 APC regulator of WNT signaling pathway 2 1.00 0.582 0.654 53
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 59
ARCN1 P48444 archain 1 Transporter 1.00 0.705 0.462 27
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846 128
ARVCF O00192 ARVCF delta catenin family member Cellular structure 5.0E-11 0.540 0.769 128
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654 179
ATPAF2 Q8N5M1 ATP synthase mitochondrial F1 complex assembly factor 2 2.2E-09 0.729 0.423 21
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923 67
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 219
B3GLCT Q6Y288 beta 3-glucosyltransferase Enzyme 7.1E-17 0.554 0.731 137
B9D2 Q9BPU9 B9 domain containing 2 Extracellular structure 5.3E-05 0.606 0.577 59
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808 180
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 254
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 147
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 140
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731 106
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808 108
CCDC22 O60826 coiled-coil domain containing 22 1.00 0.595 0.692 87
CCDC8 Q9H0W5 coiled-coil domain containing 8 0.25 0.599 0.692 48
CDC42 P60953 cell division cycle 42 Enzyme modulator 0.79 0.458 0.846 66
CDC45 O75419 cell division cycle 45 Nucleic acid binding 4.6E-05 0.588 0.692 78