Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 239 0
IFNA2 P01563 interferon alpha 2 0.442 0.885 170 0
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 151 0
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 109 0
ADORA2A P29274 adenosine A2a receptor G-protein coupled receptor 0.60 0.526 0.769 101 0
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692 67 0
SST P61278 somatostatin Signaling 0.34 0.399 0.885 56 0
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 48 0
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 44 0
HTR7 P34969 5-hydroxytryptamine receptor 7 G-protein coupled receptor 4.5E-02 0.592 0.500 39 0
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808 35 0
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692 28 0
IFNA1 P01562 interferon alpha 1 0.371 0.923 28 0
DRD5 P21918 dopamine receptor D5 G-protein coupled receptor 1.3E-16 0.603 0.423 25 0
GRIA2 P42262 glutamate ionotropic receptor AMPA type subunit 2 Ion channel 1.00 0.573 0.692 24 0
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923 15 0
LDHA P00338 lactate dehydrogenase A Enzyme 6.9E-02 0.507 0.808 15 0
VAMP2 P63027 vesicle associated membrane protein 2 0.89 0.650 0.462 15 0
DIXDC1 Q155Q3 DIX domain containing 1 Signaling 7.3E-11 0.647 0.385 15 0
PAWR Q96IZ0 pro-apoptotic WT1 regulator 9.0E-02 0.542 0.846 14 0
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538 13 0
PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 0.25 0.561 0.808 13 0
SAT1 P21673 spermidine/spermine N1-acetyltransferase 1 0.87 0.539 0.808 13 0
TPH1 P17752 tryptophan hydroxylase 1 3.2E-07 0.553 0.731 13 0