Source: GWASDB

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 7 11
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 4 1
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846 6 1
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 26 135
ACADL P28330 acyl-CoA dehydrogenase long chain Enzyme 1.7E-12 0.736 0.462 2 4
ACADS P16219 acyl-CoA dehydrogenase short chain 2.8E-06 0.663 0.538 5 9
ADAM12 O43184 ADAM metallopeptidase domain 12 Enzyme 5.7E-07 0.565 0.731 2 2
ADRB3 P13945 adrenoceptor beta 3 G-protein coupled receptor 2.5E-07 0.533 0.731 6 1
ACAN P16112 aggrecan Extracellular structure 1.00 0.528 0.846 6 8
AKT3 Q9Y243 AKT serine/threonine kinase 3 Kinase 1.00 0.512 0.808 5 3
ALDH1A2 O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 0.36 0.578 0.692 14 220
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808 10 4
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846 6 7
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 5 4
APOA1-AS APOA1 antisense RNA 0.760 0.269 3 9
APOC4-APOC2 APOC4-APOC2 readthrough (NMD candidate) 0.821 0.308 7 5
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 3 3
APOA5 Q6Q788 apolipoprotein A5 5.6E-10 0.587 0.615 9 12
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808 12 32
APOC1 P02654 apolipoprotein C1 0.22 0.581 0.577 8 7
APOC3 P02656 apolipoprotein C3 1.0E-02 0.531 0.731 3 2
APOC4 P55056 apolipoprotein C4 8.9E-08 0.743 0.385 7 4
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 9 7
ASAP3 Q8TDY4 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 8.3E-12 0.722 0.192 1 1