Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 334
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 185
IL6 P05231 interleukin 6 0.32 0.248 0.962 262
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 224
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 59
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 99
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 96
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 103
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 234
ALB P02768 albumin Transporter 0.64 0.317 0.962 122
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 128
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 127
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 90
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 65
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 65
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 178
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 86
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 85
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 109
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 97
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 40
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 31
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 85
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 77