Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
GRK2 P25098 G protein-coupled receptor kinase 2 Kinase 1.00 0.532 0.654 15
PDE5A O76074 phosphodiesterase 5A 1.1E-04 0.513 0.731 14
MCAM P43121 melanoma cell adhesion molecule Cell adhesion 1.6E-04 0.514 0.731 6
HDAC3 O15379 histone deacetylase 3 Epigenetic regulator 0.57 0.511 0.731 5
BAD Q92934 BCL2 associated agonist of cell death 4.6E-03 0.553 0.769 30
CFL1 P23528 cofilin 1 0.56 0.529 0.769 14
PRKG1 Q13976 protein kinase cGMP-dependent 1 Kinase 1.00 0.603 0.769 8
DYNLL1 P63167 dynein light chain LC8-type 1 Cellular structure 0.70 0.568 0.769 7
P2RY1 P47900 purinergic receptor P2Y1 G-protein coupled receptor 0.52 0.551 0.769 1
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 19
IGFBP3 P17936 insulin like growth factor binding protein 3 Enzyme modulator 0.91 0.439 0.808 8
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808 6
FABP4 P15090 fatty acid binding protein 4 5.2E-05 0.500 0.808 3
P2RY2 P41231 purinergic receptor P2Y2 G-protein coupled receptor 8.4E-02 0.543 0.808 2
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 48
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 69
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 60
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 44
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 27
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 20
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 20
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885 17