Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
P2RY1 P47900 purinergic receptor P2Y1 G-protein coupled receptor 0.52 0.551 0.769 1
P2RY2 P41231 purinergic receptor P2Y2 G-protein coupled receptor 8.4E-02 0.543 0.808 2
FABP4 P15090 fatty acid binding protein 4 5.2E-05 0.500 0.808 3
HDAC3 O15379 histone deacetylase 3 Epigenetic regulator 0.57 0.511 0.731 5
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808 6
MCAM P43121 melanoma cell adhesion molecule Cell adhesion 1.6E-04 0.514 0.731 6
DYNLL1 P63167 dynein light chain LC8-type 1 Cellular structure 0.70 0.568 0.769 7
IGFBP3 P17936 insulin like growth factor binding protein 3 Enzyme modulator 0.91 0.439 0.808 8
PRKG1 Q13976 protein kinase cGMP-dependent 1 Kinase 1.00 0.603 0.769 8
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 11
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 11
CFL1 P23528 cofilin 1 0.56 0.529 0.769 14
PDE5A O76074 phosphodiesterase 5A 1.1E-04 0.513 0.731 14
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885 15
GRK2 P25098 G protein-coupled receptor kinase 2 Kinase 1.00 0.532 0.654 15
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885 17
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 19
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 20
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 20
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 27
BAD Q92934 BCL2 associated agonist of cell death 4.6E-03 0.553 0.769 30
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 40
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43