Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731 21 227
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 56 3018
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846 41 15
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731 25 198
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769 16 6
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808 23 84
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885 12 13
FANCE Q9HB96 FA complementation group E 1.5E-06 0.553 0.808 11 4
FANCF Q9NPI8 FA complementation group F 0.46 0.535 0.731 11 7
FANCG O15287 FA complementation group G 2.5E-14 0.556 0.769 15 18
FANCI Q9NVI1 FA complementation group I 8.9E-37 0.543 0.731 11 28
FANCL Q9NW38 FA complementation group L Enzyme 5.9E-23 0.551 0.731 10 14
FANCM Q8IYD8 FA complementation group M Enzyme 2.4E-15 0.543 0.731 9 11
GATA1 P15976 GATA binding protein 1 0.95 0.483 0.808 22 18
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769 33 395
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692 19 90
RPL11 P62913 ribosomal protein L11 Nucleic acid binding 0.96 0.650 0.577 8 6
RPL26 P61254 ribosomal protein L26 Nucleic acid binding 0.92 0.695 0.423 6 1
RPL35A P18077 ribosomal protein L35a Nucleic acid binding 0.90 0.736 0.385 3 5
RPL5 P46777 ribosomal protein L5 Nucleic acid binding 1.00 0.617 0.615 8 16
RPS10 P46783 ribosomal protein S10 Nucleic acid binding 0.97 0.729 0.462 4 2
RPS17 P08708 ribosomal protein S17 Nucleic acid binding 0.33 0.751 0.462 3 3
RPS19 P39019 ribosomal protein S19 Nucleic acid binding 0.92 0.480 0.846 14 15
RPS24 P62847 ribosomal protein S24 Nucleic acid binding 0.68 0.695 0.423 5 9