| TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
84
|
390 |
| PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
85
|
55 |
| CDKN2A |
P42771 Q8N726
|
cyclin dependent kinase inhibitor 2A
|
|
0.39 |
0.300 |
0.885 |
22
|
83 |
| CTNNB1 |
P35222
|
catenin beta 1
|
|
1.00 |
0.303 |
0.885 |
70
|
52 |
| PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
107
|
343 |
| BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
125
|
84 |
| KRAS |
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
7.9E-04 |
0.320 |
0.923 |
66
|
35 |
| ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
23
|
28 |
| MTOR |
P42345
|
mechanistic target of rapamycin kinase
|
Kinase
|
1.00 |
0.343 |
0.885 |
86
|
26 |
| MYC |
P01106
|
MYC proto-oncogene, bHLH transcription factor
|
Transcription factor
|
1.00 |
0.344 |
0.923 |
6
|
8 |
| KIT |
P10721
|
KIT proto-oncogene, receptor tyrosine kinase
|
Kinase
|
0.98 |
0.366 |
0.808 |
21
|
66 |
| EZH2 |
Q15910
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
Epigenetic regulator
|
1.00 |
0.376 |
0.885 |
6
|
16 |
| HRAS |
P01112
|
HRas proto-oncogene, GTPase
|
Enzyme modulator
|
8.0E-02 |
0.378 |
0.885 |
71
|
21 |
| NRAS |
P01111
|
NRAS proto-oncogene, GTPase
|
Enzyme modulator
|
0.49 |
0.390 |
0.808 |
37
|
14 |
| CDK4 |
P11802
|
cyclin dependent kinase 4
|
Kinase
|
6.3E-02 |
0.412 |
0.808 |
7
|
2 |
| RAF1 |
P04049
|
Raf-1 proto-oncogene, serine/threonine kinase
|
Kinase
|
0.85 |
0.418 |
0.885 |
45
|
26 |
| GNAS |
O95467 P63092 P84996 Q5JWF2
|
GNAS complex locus
|
Enzyme modulator
|
0.68 |
0.420 |
0.885 |
60
|
27 |
| IDH1 |
O75874
|
isocitrate dehydrogenase (NADP(+)) 1
|
|
2.6E-12 |
0.424 |
0.808 |
18
|
2 |
| CREBBP |
Q92793
|
CREB binding protein
|
|
1.00 |
0.428 |
0.808 |
40
|
115 |
| RAC1 |
P63000
|
Rac family small GTPase 1
|
Enzyme modulator
|
0.76 |
0.429 |
0.962 |
5
|
7 |
| MAP2K1 |
Q02750
|
mitogen-activated protein kinase kinase 1
|
Kinase
|
0.90 |
0.439 |
0.846 |
26
|
30 |
| B2M |
P61769
|
beta-2-microglobulin
|
Immune response
|
0.56 |
0.447 |
0.846 |
12
|
6 |
| FBXW7 |
Q969H0
|
F-box and WD repeat domain containing 7
|
Enzyme modulator
|
1.00 |
0.465 |
0.808 |
18
|
7 |
| PIK3R1 |
P27986
|
phosphoinositide-3-kinase regulatory subunit 1
|
Kinase
|
1.00 |
0.477 |
0.885 |
10
|
24 |