Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CHRNB3 Q05901 cholinergic receptor nicotinic beta 3 subunit Ion channel 8.6E-06 0.705 0.308 6
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346 4
CHRNB4 P30926 cholinergic receptor nicotinic beta 4 subunit Ion channel 0.14 0.644 0.423 2
FAM53B Q14153 family with sequence similarity 53 member B 0.86 0.716 0.423 1
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462 7
GALR1 P47211 galanin receptor 1 G-protein coupled receptor 5.3E-04 0.656 0.500 1
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577 11
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577 3
NSF P46459 N-ethylmaleimide sensitive factor, vesicle fusing ATPase Enzyme 1.8E-02 0.659 0.577 1
SNORD15A small nucleolar RNA, C/D box 15A 0.653 0.577 1
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615 6
NCS1 P62166 neuronal calcium sensor 1 0.66 0.656 0.615 3
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654 12
CAMK4 Q16566 calcium/calmodulin dependent protein kinase IV Kinase 0.51 0.621 0.654 1
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692 12
MC4R P32245 melanocortin 4 receptor G-protein coupled receptor 9.2E-04 0.535 0.692 4
CHRNA3 P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 1.4E-07 0.588 0.692 3
OPRD1 P41143 opioid receptor delta 1 G-protein coupled receptor 3.3E-03 0.604 0.731 2
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769 16
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 9
SLC18A2 Q05940 solute carrier family 18 member A2 Transporter 7.6E-02 0.554 0.769 8
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 26
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808 12
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 7