Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ATG5 Q9H1Y0 autophagy related 5 Transporter 0.98 0.462 0.885 3
ATG7 O95352 autophagy related 7 Enzyme 7.4E-12 0.505 0.769 11
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 40
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846 26
C1QA P02745 complement C1q A chain 3.8E-03 0.623 0.654 3
C4A P0C0L4 P0C0L5 complement C4A (Rodgers blood group) Enzyme modulator 1.5E-11 0.563 0.769 1
C4B P0C0L4 P0C0L5 complement C4B (Chido blood group) Enzyme modulator 0.83 0.603 0.808 1
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769 21
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885 14
DEF6 Q9H4E7 DEF6 guanine nucleotide exchange factor Nucleic acid binding 1.00 0.751 0.346 1
DNASE1 P24855 deoxyribonuclease 1 7.0E-21 0.505 0.846 1
POLB P06746 DNA polymerase beta Enzyme 3.4E-05 0.606 0.654 2
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 21
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 49
FCGR2B P31994 Fc fragment of IgG receptor IIb Cell adhesion 0.46 0.522 0.846 5
GADD45A P24522 growth arrest and DNA damage inducible alpha 4.4E-02 0.526 0.769 1
IKZF3 Q9UKT9 IKAROS family zinc finger 3 Transcription factor 0.98 0.608 0.692 1
INPP5D Q92835 inositol polyphosphate-5-phosphatase D 0.97 0.558 0.731 2
IFIH1 Q9BYX4 interferon induced with helicase C domain 1 7.0E-44 0.471 0.808 1
JAK1 P23458 Janus kinase 1 Kinase 1.00 0.474 0.769 1
JUNB P17275 JunB proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.86 0.467 0.769 3
LBR Q14739 lamin B receptor Enzyme 0.18 0.473 0.808 3
LYN P07948 LYN proto-oncogene, Src family tyrosine kinase Kinase 1.00 0.603 0.615 4
MAN2A1 Q16706 mannosidase alpha class 2A member 1 1.6E-10 0.705 0.538 2