Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2475 28
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2245 232
IL6 P05231 interleukin 6 0.32 0.248 0.962 2132 21
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1604 22
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1410 15
IFNG P01579 interferon gamma 0.47 0.288 0.962 1361 10
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1334 32
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1173 9
ALB P02768 albumin Transporter 0.64 0.317 0.962 1089 13
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 1043 27
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 1030 52
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 1011 29
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 994 8
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 972 97
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 951 4
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 932 19
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 926 22
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 886 50
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962 762 4
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 702 42
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 664 32
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 647 13
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 641 11