Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
AFP P02771 alpha fetoprotein Transporter 1.1E-11 0.429 0.885 374 6
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 1011 29
ARAF P10398 A-Raf proto-oncogene, serine/threonine kinase Kinase 0.96 0.619 0.654 48 2
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808 165 2
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 563 65
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923 223 7
AURKB Q96GD4 aurora kinase B Kinase 4.5E-03 0.510 0.769 154 3
B3GAT1 Q9P2W7 beta-1,3-glucuronyltransferase 1 Enzyme 0.14 0.494 0.769 191 0
BCAR1 P56945 BCAR1 scaffold protein, Cas family member 1.00 0.518 0.846 163 1
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885 319 6
CAD P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 1.00 0.482 0.846 216 3
CD38 P28907 CD38 molecule Enzyme 2.3E-06 0.407 0.885 463 7
CRYBG1 Q9Y4K1 crystallin beta-gamma domain containing 1 3.5E-33 0.743 0.462 18 1
CSE1L P55060 chromosome segregation 1 like Enzyme modulator 1.00 0.521 0.808 157 0
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 552 2
CTNND1 O60716 catenin delta 1 Cellular structure 1.00 0.500 0.808 174 1
DLEU7 Q6UYE1 deleted in lymphocytic leukemia 7 0.18 0.705 0.346 21 1
DMD P11532 dystrophin 1.00 0.423 0.923 360 36
ENDOU P21128 endonuclease, poly(U) specific 3.2E-14 0.682 0.423 41 0
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846 636 9
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 942 62
EXOSC6 Q5RKV6 exosome component 6 Enzyme 0.52 0.674 0.462 42 0
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 546 5
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923 652 15