Source: GENOMICS_ENGLAND

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
COL10A1 Q03692 collagen type X alpha 1 chain Extracellular structure 3.0E-05 0.619 0.500 2
CTSK P43235 cathepsin K Enzyme 3.1E-05 0.497 0.808 2
CUL7 Q14999 cullin 7 2.6E-21 0.633 0.500 2
DDR2 Q16832 discoidin domain receptor tyrosine kinase 2 Kinase 0.55 0.541 0.769 2
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769 2
FAM20C Q8IXL6 FAM20C golgi associated secretory pathway kinase 0.31 0.578 0.731 2
GPC6 Q9Y625 glypican 6 0.14 0.626 0.654 2
KIF22 Q14807 kinesin family member 22 Cellular structure 9.2E-10 0.552 0.654 2
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 2
OBSL1 O75147 obscurin like cytoskeletal adaptor 1 1.0E-25 0.686 0.308 2
PAPSS2 O95340 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Enzyme 2.0E-10 0.682 0.462 2
SH3PXD2B A1X283 SH3 and PX domains 2B 4.2E-03 0.631 0.577 2
SLC35D1 Q9NTN3 solute carrier family 35 member D1 Transporter 3.6E-04 0.736 0.385 2
SULF1 Q8IWU6 sulfatase 1 Enzyme 1.4E-03 0.585 0.538 2
TRIP11 Q15643 thyroid hormone receptor interactor 11 1.7E-12 0.595 0.654 2
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808 2
ACP5 P13686 acid phosphatase 5, tartrate resistant 7.9E-02 0.561 0.731 3
ANKH Q9HCJ1 ANKH inorganic pyrophosphate transport regulator Transporter 0.28 0.606 0.692 3
CANT1 Q8WVQ1 calcium activated nucleotidase 1 2.5E-06 0.619 0.731 3
CHST14 Q8NCH0 carbohydrate sulfotransferase 14 Enzyme 0.45 0.638 0.654 3
CHST3 Q7LGC8 carbohydrate sulfotransferase 3 7.2E-03 0.517 0.846 3
EIF2AK3 Q9NZJ5 eukaryotic translation initiation factor 2 alpha kinase 3 Kinase 2.8E-03 0.501 0.808 3
EXT2 Q93063 exostosin glycosyltransferase 2 Enzyme 1.3E-09 0.576 0.654 3
IFT122 Q9HBG6 intraflagellar transport 122 2.4E-24 0.560 0.846 3