Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 340 9
IL6 P05231 interleukin 6 0.32 0.248 0.962 270 4
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 239 0
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 232 407
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 231 5
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 179 27
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 171 2
IFNG P01579 interferon gamma 0.47 0.288 0.962 167 1
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 151 0
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 147 48
ALB P02768 albumin Transporter 0.64 0.317 0.962 123 9
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 115 30
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 113 95
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 109 7
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 109 1
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 103 3
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 95 596
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 80 6
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 80 3
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 70 0
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 63 1
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 57 9
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 44 22
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 31 16