Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885 20
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885 17
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885 15
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 15
AQP1 P29972 aquaporin 1 (Colton blood group) Ion channel 2.6E-07 0.467 0.885 9
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 8
CCL3 P10147 C-C motif chemokine ligand 3 Signaling 0.35 0.460 0.885 8
SRC P12931 SRC proto-oncogene, non-receptor tyrosine kinase Kinase 1.00 0.467 0.885 7
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885 7
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 2
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 39
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 26
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 22
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846 12
PGF P49763 placental growth factor Signaling 0.13 0.460 0.846 11
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846 9
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846 9
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846 8
ACAN P16112 aggrecan Extracellular structure 1.00 0.528 0.846 7
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846 7
GRN P28799 granulin precursor 7.0E-02 0.435 0.846 1
SLC6A8 P48029 solute carrier family 6 member 8 Transporter 1.00 0.476 0.846 1
SSTR4 P31391 somatostatin receptor 4 G-protein coupled receptor 3.7E-13 0.469 0.846 1
CX3CL1 P78423 C-X3-C motif chemokine ligand 1 Signaling 0.61 0.478 0.808 27