Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 23
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846 23
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808 22
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 22
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808 21
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 21
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923 20
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885 20
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808 20
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885 19
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885 18
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 18
UCP2 P55851 uncoupling protein 2 Transporter 1.5E-10 0.493 0.808 18
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 17
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923 17
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 17
ADRB1 P08588 adrenoceptor beta 1 G-protein coupled receptor 2.9E-06 0.555 0.769 16
GRK2 P25098 G protein-coupled receptor kinase 2 Kinase 1.00 0.532 0.654 15
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 15
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808 14
BNIP3 Q12983 BCL2 interacting protein 3 2.0E-05 0.520 0.731 14
ECE1 P42892 endothelin converting enzyme 1 Enzyme 0.96 0.541 0.769 14
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846 14
BIRC5 O15392 baculoviral IAP repeat containing 5 Enzyme modulator 5.6E-02 0.495 0.731 13