Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 535 18
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923 520 17
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 517 111
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 501 29
SST P61278 somatostatin Signaling 0.34 0.399 0.885 495 4
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 470 55
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846 436 6
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 435 5
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846 412 8
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885 411 22
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885 408 19
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808 405 12
TTR P02766 transthyretin Transporter 0.52 0.423 0.885 404 48
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885 404 9
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885 400 7
S100A1 P23297 S100 calcium binding protein A1 Calcium-binding protein 6.0E-03 0.421 0.846 392 1
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 389 26
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808 383 23
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769 382 9
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808 378 9
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 377 33
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885 367 45
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808 348 10
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846 345 19