Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 960 48
IL2 P60568 interleukin 2 0.48 0.336 0.885 950 5
LEP P41159 leptin 0.46 0.349 0.846 931 15
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962 875 79
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 873 39
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 824 13
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 819 26
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 794 14
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 783 28
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 770 23
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 750 18
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923 739 23
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 722 24
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 702 98
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 701 52
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 693 64
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 687 4
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 668 32
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 664 387
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 646 11
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846 581 6
MBL2 P11226 mannose binding lectin 2 Receptor 2.7E-03 0.390 0.846 563 21