Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 59
CDH1 P12830 cadherin 1 0.15 0.401 0.808 57
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 57
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 53
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 52
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 52
TFRC P02786 transferrin receptor Enzyme 7.0E-05 0.437 0.885 51
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923 50
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885 49
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 46
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 45
CYP2A6 P11509 cytochrome P450 family 2 subfamily A member 6 5.4E-09 0.556 0.731 44
BIRC5 O15392 baculoviral IAP repeat containing 5 Enzyme modulator 5.6E-02 0.495 0.731 42
DPYD Q12882 dihydropyrimidine dehydrogenase Enzyme 3.4E-22 0.493 0.846 42
ATP7B P35670 ATPase copper transporting beta Transporter 4.8E-30 0.529 0.654 41
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 39
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769 39
SPARC P09486 secreted protein acidic and cysteine rich Signaling 0.89 0.445 0.846 39
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 38
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808 36
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 36
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885 35
PRKCE Q02156 protein kinase C epsilon Kinase 1.00 0.597 0.692 35
SELENOP P49908 selenoprotein P Extracellular structure 8.3E-07 0.545 0.769 35