Source: GENOMICS_ENGLAND

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CDH2 P19022 cadherin 2 0.99 0.535 0.731 8
DLL1 O00548 delta like canonical Notch ligand 1 1.00 0.492 0.808 8
FDFT1 P37268 farnesyl-diphosphate farnesyltransferase 1 4.1E-15 0.621 0.615 8
MED12L Q86YW9 mediator complex subunit 12L Transcription factor 1.00 0.839 0.269 8
MED13 Q9UHV7 mediator complex subunit 13 1.00 0.711 0.538 8
PCYT2 Q99447 phosphate cytidylyltransferase 2, ethanolamine Enzyme 8.6E-04 0.821 0.192 8
PIGP P57054 phosphatidylinositol glycan anchor biosynthesis class P 1.9E-03 0.633 0.462 8
PIGU Q9H490 phosphatidylinositol glycan anchor biosynthesis class U 1.9E-05 0.670 0.462 8
PQBP1 O60828 polyglutamine binding protein 1 Transcription factor 0.79 0.570 0.654 8
SDCCAG8 Q86SQ7 serologically defined colon cancer antigen 8 1.2E-11 0.619 0.577 8
TET3 O43151 tet methylcytosine dioxygenase 3 1.00 0.633 0.615 8
CACNA1E Q15878 calcium voltage-gated channel subunit alpha1 E Ion channel 1.00 0.650 0.577 7
DDX6 P26196 DEAD-box helicase 6 1.00 0.663 0.385 7
DHPS P49366 deoxyhypusine synthase 1.6E-04 0.670 0.538 7
FCSK Q8N0W3 fucose kinase Kinase 1.0E-29 0.769 0.192 7
IQSEC1 Q6DN90 IQ motif and Sec7 domain ArfGEF 1 1.00 0.736 0.346 7
KAT8 Q9H7Z6 lysine acetyltransferase 8 0.22 0.592 0.654 7
KDM3B Q7LBC6 lysine demethylase 3B Epigenetic regulator 1.00 0.686 0.500 7
KDM5C P41229 lysine demethylase 5C 1.00 0.581 0.538 7
LNPK Q9C0E8 lunapark, ER junction formation factor 6.2E-04 0.716 0.346 7
PNPT1 Q8TCS8 polyribonucleotide nucleotidyltransferase 1 Enzyme 4.0E-04 0.653 0.462 7
PPP2CA P67775 protein phosphatase 2 catalytic subunit alpha 0.99 0.608 0.769 7
PUM1 Q14671 pumilio RNA binding family member 1 Nucleic acid binding 1.00 0.653 0.654 7
SMARCD1 Q96GM5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 Nucleic acid binding 1.00 0.695 0.385 7