Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IKBKB O14920 inhibitor of nuclear factor kappa B kinase subunit beta Kinase 0.99 0.506 0.846 11
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808 11
SELL P14151 selectin L 5.0E-07 0.505 0.846 11
CCKBR P32239 cholecystokinin B receptor G-protein coupled receptor 2.1E-06 0.573 0.615 10
CRHR2 Q13324 corticotropin releasing hormone receptor 2 G-protein coupled receptor 8.5E-17 0.584 0.731 10
HAVCR1 Q96D42 hepatitis A virus cellular receptor 1 8.5E-07 0.489 0.885 10
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923 9
CXCR2 P25025 C-X-C motif chemokine receptor 2 G-protein coupled receptor 1.4E-02 0.445 0.923 8
TLR3 O15455 toll like receptor 3 Receptor 1.6E-07 0.427 0.885 8
APLN Q9ULZ1 apelin 0.46 0.497 0.769 7
ATP5F1D P30049 ATP synthase F1 subunit delta Transporter 7.4E-02 0.674 0.500 7
ADRB3 P13945 adrenoceptor beta 3 G-protein coupled receptor 2.5E-07 0.533 0.731 6
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 6
UCN P55089 urocortin Signaling 0.45 0.539 0.769 6
ARRB1 P49407 arrestin beta 1 Enzyme modulator 0.99 0.588 0.846 5
RETN Q9HD89 resistin 3.7E-02 0.454 0.808 5
SI P14410 sucrase-isomaltase Enzyme 3.9E-60 0.569 0.692 5
BMP6 P22004 bone morphogenetic protein 6 Signaling 0.76 0.531 0.808 4
CCR1 P32246 C-C motif chemokine receptor 1 G-protein coupled receptor 0.39 0.531 0.769 3
ICOS Q9Y6W8 inducible T cell costimulator 3.1E-02 0.502 0.731 3
LCT P09848 lactase Enzyme 6.0E-02 0.581 0.808 3
TACR2 P21452 tachykinin receptor 2 G-protein coupled receptor 8.8E-05 0.700 0.500 3
TFF1 P04155 trefoil factor 1 Signaling 8.9E-04 0.529 0.769 3
CHUK O15111 component of inhibitor of nuclear factor kappa B kinase complex Kinase 0.99 0.556 0.731 2