Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 137
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 135
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 135
PLEC Q15149 plectin Cellular structure 8.3E-12 0.523 0.808 133
PRDM16 Q9HAZ2 PR/SET domain 16 1.00 0.522 0.808 132
VPS13B Q7Z7G8 vacuolar protein sorting 13 homolog B 2.5E-45 0.579 0.769 127
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 122
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731 121
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 120
HNF4A P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 0.15 0.461 0.808 118
RFWD3 Q6PCD5 ring finger and WD repeat domain 3 Enzyme 3.5E-10 0.569 0.731 116
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846 114
AUTS2 Q8WXX7 activator of transcription and developmental regulator AUTS2 1.00 0.569 0.846 112
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846 111
KANSL1 Q7Z3B3 KAT8 regulatory NSL complex subunit 1 1.00 0.592 0.731 110
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 108
CPLX1 O14810 complexin 1 0.82 0.576 0.654 107
VAC14 Q08AM6 VAC14 component of PIKFYVE complex Receptor 0.19 0.588 0.731 106
ARID2 Q68CP9 AT-rich interaction domain 2 1.00 0.543 0.808 105
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808 105
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808 104
RNASEH2B Q5TBB1 ribonuclease H2 subunit B 3.3E-09 0.595 0.615 99
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769 97
SCO2 O43819 synthesis of cytochrome C oxidase 2 Enzyme 7.5E-07 0.479 0.846 97