Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ADORA2A P29274 adenosine A2a receptor G-protein coupled receptor 0.60 0.526 0.769 98
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 96
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 92
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 87
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 86
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 85
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 79
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 76
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 76
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 72
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 70
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808 67
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846 67
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 65
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846 60
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 59
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885 59
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 57
KNG1 P01042 kininogen 1 Enzyme modulator 3.2E-10 0.481 0.885 56
PRKCD Q05655 protein kinase C delta Kinase 1.00 0.480 0.846 55
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923 50
NDRG1 Q92597 N-myc downstream regulated 1 Enzyme 1.1E-02 0.488 0.731 49
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 48
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769 48