Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
PAFAH1B1 P43034 platelet activating factor acetylhydrolase 1b regulatory subunit 1 1.00 0.504 0.769 219 103
MKS1 Q9NXB0 MKS transition zone complex subunit 1 Extracellular structure 3.4E-16 0.505 0.769 231 57
ACTG2 P63267 actin gamma 2, smooth muscle Cellular structure 7.1E-02 0.505 0.808 205 17
MYLK Q15746 myosin light chain kinase Kinase 9.2E-12 0.510 0.846 199 28
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769 205 11
SEMA3E O15041 semaphorin 3E Signaling 8.7E-09 0.515 0.769 184 8
TWIST2 Q8WVJ9 twist family bHLH transcription factor 2 Transcription factor 0.56 0.518 0.731 198 7
HIC1 Q14526 HIC ZBTB transcriptional repressor 1 Transcription factor 0.13 0.522 0.615 163 4
SLC19A1 P41440 solute carrier family 19 member 1 Transporter 6.5E-06 0.523 0.692 155 47
WDR35 Q9P2L0 WD repeat domain 35 1.0E-22 0.525 0.692 188 30
MYH11 P35749 myosin heavy chain 11 0.77 0.528 0.731 161 25
YWHAE P62258 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon Chaperone 0.98 0.530 0.692 176 6
EYA1 Q99502 EYA transcriptional coactivator and phosphatase 1 0.95 0.531 0.731 168 36
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654 172 23
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 0.534 0.731 159 17
SDS P20132 serine dehydratase Enzyme 1.4E-04 0.534 0.769 139 7
GYPA P02724 glycophorin A (MNS blood group) 1.1E-03 0.538 0.885 136 5
RAB23 Q9ULC3 RAB23, member RAS oncogene family 5.6E-03 0.541 0.654 144 5
PORCN Q9H237 porcupine O-acyltransferase Enzyme 1.00 0.545 0.692 162 9
NFIX Q14938 nuclear factor I X Nucleic acid binding 1.00 0.547 0.769 183 33
GPC4 O75487 glypican 4 0.93 0.547 0.769 181 8
DACT1 Q9NYF0 dishevelled binding antagonist of beta catenin 1 0.40 0.547 0.692 134 4
DYNC2H1 Q8NCM8 dynein cytoplasmic 2 heavy chain 1 Enzyme 1.1E-44 0.555 0.731 136 159
CHUK O15111 component of inhibitor of nuclear factor kappa B kinase complex Kinase 0.99 0.556 0.731 125 6