Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 28
CX3CL1 P78423 C-X3-C motif chemokine ligand 1 Signaling 0.61 0.478 0.808 27
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 27
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 27
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 27
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 26
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 26
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846 26
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 26
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 26
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 26
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 26
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 26
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 26
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 26
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885 26
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846 25
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 25
IFNG P01579 interferon gamma 0.47 0.288 0.962 25
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 25
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 25
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846 24
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 24
HAMP P81172 hepcidin antimicrobial peptide 8.2E-03 0.433 0.846 24