Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885 504 43
ATN1 P54259 atrophin 1 1.00 0.409 0.885 499 6
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 496 29
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 487 48
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 480 32
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885 480 10
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808 470 23
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 464 9
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846 457 17
TLR9 Q9NR96 toll like receptor 9 9.8E-06 0.411 0.885 457 11
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 452 109
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 450 16
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885 445 10
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885 444 5
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808 443 30
GCG P01275 glucagon 3.5E-02 0.431 0.885 441 10
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 440 33
MIR34A microRNA 34a 0.421 0.846 428 5
IL15 P40933 interleukin 15 0.71 0.422 0.846 426 10
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846 415 59
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885 408 20
INS P01308 insulin 0.30 0.445 0.923 405 37
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808 405 1
TRPV1 Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 1.0E-16 0.446 0.885 404 6