Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923 108 98
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731 108 72
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 107 2
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885 104 0
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 103 4
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 103 3
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577 102 7
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 101 18
ADORA2A P29274 adenosine A2a receptor G-protein coupled receptor 0.60 0.526 0.769 101 0
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885 100 3
TRH P20396 thyrotropin releasing hormone 8.9E-04 0.519 0.846 100 1
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 99 10
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 98 61
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 98 8
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885 97 0
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 96 6
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 95 596
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 95 5
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 94 70
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 93 98
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885 93 2
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 93 1
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 92 30
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 91 10