Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769 90 103
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 90 28
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 90 9
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 89 14
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 89 9
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 89 2
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 89 1
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 87 79
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885 85 5
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 84 4
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 83 37
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808 83 5
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 82 6
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 81 2
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 81 1
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 80 6
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 80 3
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808 79 29
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 78 47
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846 78 18
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885 77 931
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923 77 0
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846 76 24
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846 75 62