| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases |
|---|---|---|---|---|---|---|---|
| MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 | 86 |
| PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 | 76 |
| BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 | 60 |
| XDH | P47989 | xanthine dehydrogenase | Enzyme | 2.6E-22 | 0.529 | 0.846 | 38 |
| MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 | 25 |
| CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | 20 | |
| DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 | 18 |
| CCNE1 | P24864 | cyclin E1 | Enzyme modulator | 0.97 | 0.538 | 0.731 | 11 |
| COL18A1 | P39060 | collagen type XVIII alpha 1 chain | 1.7E-10 | 0.449 | 0.808 | 11 | |
| JAK3 | P52333 | Janus kinase 3 | Kinase | 5.9E-06 | 0.505 | 0.731 | 6 |
| APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | 3 | |
| MEN1 | O00255 | menin 1 | 1.00 | 0.444 | 0.808 | 2 |