Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 40
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 38
CASP9 P55211 caspase 9 Enzyme 7.4E-06 0.458 0.808 37
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846 31
GSR P00390 glutathione-disulfide reductase Enzyme 1.3E-06 0.494 0.846 31
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885 30
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 26
CCL11 P51671 C-C motif chemokine ligand 11 Signaling 1.0E-02 0.473 0.885 16
AKR1B1 P15121 aldo-keto reductase family 1 member B Enzyme 2.0E-05 0.491 0.885 15
SLC9A1 P19634 solute carrier family 9 member A1 Transporter 0.79 0.550 0.731 15
GPX1 P07203 glutathione peroxidase 1 Enzyme 3.9E-05 0.458 0.923 13
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846 8
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 7
SLC2A3 P11169 solute carrier family 2 member 3 Transporter 1.0E-02 0.534 0.769 5
CCK P06307 cholecystokinin 3.3E-05 0.453 0.846 4
CRYAB P02511 crystallin alpha B 2.2E-02 0.515 0.731 4
GJA8 P48165 gap junction protein alpha 8 Cell-cell junction 2.2E-03 0.587 0.577 4
CRYAA A0A140G945 P02489 crystallin alpha A 0.17 0.653 0.385 3
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846 3
CRYBA4 P53673 crystallin beta A4 3.5E-09 0.716 0.269 1
CRYGD P07320 crystallin gamma D 3.0E-04 0.510 0.808 1
CTH P32929 cystathionine gamma-lyase Enzyme 7.5E-08 0.578 0.615 1