Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7498
Gene Symbol: XDH
XDH
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Therapeutic RGD The effects of Nigella sativa oil, thymoquinone, propolis, and caffeic acid phenethyl ester on radiation-induced cataract. 25860848

2016

Entrez Id: 2539
Gene Symbol: G6PD
G6PD
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Therapeutic RGD Grape seed extract and zinc containing nutritional food supplement prevents onset and progression of age-related cataract in wistar rats. 24886740

2014

Entrez Id: 102
Gene Symbol: ADAM10
ADAM10
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Excessive hydrogen peroxide enhances the attachment of amyloid β1-42 in the lens epithelium of UPL rats, a hereditary model for cataracts. 23941810

2014

Entrez Id: 2936
Gene Symbol: GSR
GSR
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Therapeutic RGD Ameliorative effect of acetyl-L-carnitine and/or nifedipine against selenite-induced cataractogenesis in young albino rats. 24530554

2014

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Therapeutic RGD Chaperone peptides of α-crystallin inhibit epithelial cell apoptosis, protein insolubilization, and opacification in experimental cataracts. 23508955

2013

Entrez Id: 2876
Gene Symbol: GPX1
GPX1
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Effect of blood-retinal barrier development on formation of selenite nuclear cataract in rat. 23194826

2013

Entrez Id: 842
Gene Symbol: CASP9
CASP9
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Therapeutic RGD Chaperone peptides of α-crystallin inhibit epithelial cell apoptosis, protein insolubilization, and opacification in experimental cataracts. 23508955

2013

Entrez Id: 6356
Gene Symbol: CCL11
CCL11
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Nicotine exposure exacerbates development of cataracts in a type 1 diabetic rat model. 23049540

2012

Entrez Id: 6548
Gene Symbol: SLC9A1
SLC9A1
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Na+/H+-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis. 22407349

2012

Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Therapeutic RGD Protective effects and mechanism of tetramethylpyrazine against lens opacification induced by sodium selenite in rats. 21635889

2011

Entrez Id: 3606
Gene Symbol: IL18
IL18
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Involvement of interleukin 18 in lens opacification of Otsuka Long-Evans Tokushima Fatty rats, a model of human type 2 diabetes. 21591858

2011

Entrez Id: 1410
Gene Symbol: CRYAB
CRYAB
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Changes in physicochemical parameters and alpha-crystallin expression in the lens during cataract development in OXYS rats. 5. 19120020

2008

Entrez Id: 231
Gene Symbol: AKR1B1
AKR1B1
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Therapeutic RGD Acetic acid aldose reductase inhibitors bearing a five-membered heterocyclic core with potent topical activity in a visual impairment rat model. 18452283

2008

Entrez Id: 1409
Gene Symbol: CRYAA
CRYAA
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Changes in physicochemical parameters and alpha-crystallin expression in the lens during cataract development in OXYS rats. 5. 19120020

2008

Entrez Id: 3606
Gene Symbol: IL18
IL18
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Involvement of interleukin 18 in cataract development in hereditary cataract UPL rats. 18006521

2007

Entrez Id: 231
Gene Symbol: AKR1B1
AKR1B1
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Topical aldose reductase inhibitor formulations for effective lens drug delivery in a rat model for sugar cataracts. 17444799

2007

Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Characterizing a rat Brca2 knockout model. 16964288

2007

Entrez Id: 885
Gene Symbol: CCK
CCK
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD The antagonism of cholecystokinin octapeptide-8 to the peroxynitrite oxidation on a diabetic cataractal rat model. 16989746

2006

Entrez Id: 2222
Gene Symbol: FDFT1
FDFT1
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat. 16440058

2006

Entrez Id: 2700
Gene Symbol: GJA3
GJA3
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD New genetic model rat for congenital cataracts due to a connexin 46 (Gja3 ) mutation. 16271086

2005

Entrez Id: 1491
Gene Symbol: CTH
CTH
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Age-associated oxidative damage leads to absence of gamma-cystathionase in over 50% of rat lenses: relevance in cataractogenesis. 15683713

2005

Entrez Id: 1409
Gene Symbol: CRYAA
CRYAA
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Comparison of post-translational modifications of alpha A-crystallin from normal and hereditary cataract rats. 15042443

2004

Entrez Id: 6515
Gene Symbol: SLC2A3
SLC2A3
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Expression patterns for glucose transporters GLUT1 and GLUT3 in the normal rat lens and in models of diabetic cataract. 12882795

2003

Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Alteration of cadherin in dexamethasone-induced cataract organ-cultured rat lens. 12714641

2003

Entrez Id: 2703
Gene Symbol: GJA8
GJA8
CUI: C0029531
Disease: Other cataract
Other cataract
0.200 Biomarker RGD Mapping of A gene responsible for cataract formation and its modifier in the UPL rat. 12356818

2002