Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 133 7
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 115 1
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808 109 4
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 109 0
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885 93 2
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 75 6
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 60 79
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577 53 28
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846 50 34
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692 48 2
CHRM2 P08172 cholinergic receptor muscarinic 2 G-protein coupled receptor 0.18 0.585 0.615 43 3
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885 42 633
GRIK2 Q13002 glutamate ionotropic receptor kainate type subunit 2 Ion channel 1.00 0.561 0.769 41 3
PCDH15 Q96QU1 protocadherin related 15 8.0E-25 0.601 0.577 36 118
PRKCE Q02156 protein kinase C epsilon Kinase 1.00 0.597 0.692 35 50
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731 34 16
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846 32 29
SYNE1 Q8NF91 spectrin repeat containing nuclear envelope protein 1 3.2E-52 0.511 0.846 30 72
CDH13 P55290 cadherin 13 7.1E-04 0.501 0.846 26 34
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923 25 1
TTC21B Q7Z4L5 tetratricopeptide repeat domain 21B 2.7E-26 0.619 0.654 23 24
ABCC4 O15439 ATP binding cassette subfamily C member 4 Transporter 1.1E-07 0.536 0.769 22 8
GRM7 Q14831 glutamate metabotropic receptor 7 G-protein coupled receptor 1.00 0.628 0.538 20 11
ZNF804A Q7Z570 zinc finger protein 804A 5.5E-03 0.647 0.654 20 10