Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.400 Biomarker CTD_human Imaging gene-substance interactions: the effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward. 16901644

2006

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.390 Biomarker CTD_human Serotonin transporter promoter region polymorphisms do not influence treatment response to escitalopram in patients with major depression. 19272758

2009

Entrez Id: 1268
Gene Symbol: CNR1
CNR1
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.340 Biomarker CTD_human Association between a cannabinoid receptor gene (CNR1) polymorphism and cannabinoid-induced alterations of the auditory event-related P300 potential. 21513772

2011

Entrez Id: 1268
Gene Symbol: CNR1
CNR1
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.340 Biomarker CTD_human Chronic unpredictable stress enhances cocaine-conditioned place preference in type 1 cannabinoid receptor knockout mice. 18690112

2008

Entrez Id: 1268
Gene Symbol: CNR1
CNR1
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.340 Biomarker CTD_human Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. 9888857

1999

Entrez Id: 1012
Gene Symbol: CDH13
CDH13
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.330 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 2166
Gene Symbol: FAAH
FAAH
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.330 Biomarker CTD_human Divergent effects of genetic variation in endocannabinoid signaling on human threat- and reward-related brain function. 19103437

2009

Entrez Id: 2166
Gene Symbol: FAAH
FAAH
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.330 Biomarker CTD_human A missense mutation in human fatty acid amide hydrolase associated with problem drug use. 12060782

2002

Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.310 Biomarker CTD_human Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators. 27192616

2016

Entrez Id: 2917
Gene Symbol: GRM7
GRM7
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.310 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 4852
Gene Symbol: NPY
NPY
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.310 Biomarker CTD_human Neuropeptide Y augments cocaine self-administration and cocaine-induced hyperlocomotion in rats. 19063928

2009

Entrez Id: 5087
Gene Symbol: PBX1
PBX1
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 9271
Gene Symbol: PIWIL1
PIWIL1
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 1769
Gene Symbol: DNAH8
DNAH8
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 51082
Gene Symbol: POLR1D
POLR1D
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 64131
Gene Symbol: XYLT1
XYLT1
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 7260
Gene Symbol: EIPR1
EIPR1
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 9748
Gene Symbol: SLK
SLK
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 167465
Gene Symbol: ZNF366
ZNF366
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 57733
Gene Symbol: GBA3
GBA3
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 25807
Gene Symbol: RHBDD3
RHBDD3
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 114786
Gene Symbol: XKR4
XKR4
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 80206
Gene Symbol: FHOD3
FHOD3
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010

Entrez Id: 55742
Gene Symbol: PARVA
PARVA
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders
0.300 Biomarker CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672

2010