Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 241 7
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 231 5
IFNG P01579 interferon gamma 0.47 0.288 0.962 167 1
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 115 30
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 115 1
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923 108 98
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 95 5
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 92 30
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 68 172
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 57 9
IFNB1 P01574 interferon beta 1 0.421 0.846 49 1
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 42 22
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 41 27
NECTIN2 Q92692 nectin cell adhesion molecule 2 0.97 0.575 0.769 40 64
SLC11A1 P49279 solute carrier family 11 member 1 Transporter 1.5E-19 0.525 0.846 40 1
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885 38 38
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 35 0
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885 31 30
TYK2 P29597 tyrosine kinase 2 Kinase 4.5E-08 0.505 0.769 31 15
GC P02774 GC vitamin D binding protein Transporter 2.7E-11 0.489 0.885 31 9
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923 30 108
CD40 P25942 CD40 molecule 0.85 0.396 0.846 29 9
TNFAIP3 P21580 TNF alpha induced protein 3 Enzyme 1.00 0.481 0.808 28 16
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885 27 0