Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 94
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 71
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 49
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 47
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 40
CASP9 P55211 caspase 9 Enzyme 7.4E-06 0.458 0.808 37
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 35
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 34
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 26
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923 24
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 24
CASP12 Q6UXS9 caspase 12 (gene/pseudogene) 1.3E-04 0.638 0.808 23
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808 22
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808 20
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 20
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692 19
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808 17
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885 17
PDGFB P01127 platelet derived growth factor subunit B Signaling 0.77 0.488 0.846 17