Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 184 9
IFNA2 P01563 interferon alpha 2 0.442 0.885 170 0
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168 2
IFNG P01579 interferon gamma 0.47 0.288 0.962 167 1
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 130 54
ALB P02768 albumin Transporter 0.64 0.317 0.962 123 9
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885 65 229
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 62 3
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 58 15
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 48 0
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 42 277
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 40 44
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 25 70
PML P29590 promyelocytic leukemia 0.21 0.477 0.846 21 10
HLA-C P10321 major histocompatibility complex, class I, C 1.6E-06 0.415 0.846 20 32
VCP P55072 valosin containing protein 1.00 0.469 0.923 19 17
PTGIS Q16647 prostaglandin I2 synthase 1.2E-09 0.617 0.654 14 4
PTGER3 P43115 prostaglandin E receptor 3 G-protein coupled receptor 0.37 0.601 0.731 13 2
CELF2 O95319 CUGBP Elav-like family member 2 1.00 0.628 0.692 9 16
NEDD4 P46934 NEDD4 E3 ubiquitin protein ligase Enzyme 8.7E-13 0.569 0.846 9 4
CUL4A Q13619 cullin 4A Enzyme 1.00 0.597 0.654 9 4
ELMO1 Q92556 engulfment and cell motility 1 Signaling 0.90 0.608 0.615 8 26
PSMC5 P62195 proteasome 26S subunit, ATPase 5 Enzyme 0.93 0.686 0.538 8 0
COPS5 Q92905 COP9 signalosome subunit 5 Enzyme 1.00 0.566 0.769 6 1