Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 72
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 71
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 55
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 47
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 46
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 41
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 38
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 37
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885 33
GSR P00390 glutathione-disulfide reductase Enzyme 1.3E-06 0.494 0.846 31
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885 30
BAD Q92934 BCL2 associated agonist of cell death 4.6E-03 0.553 0.769 30
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 30
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 30
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 24
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 23
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 23