Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Therapeutic RGD S-Allylmercaptocysteine Attenuates  Cisplatin-Induced Nephrotoxicity through  Suppression of Apoptosis, Oxidative Stress, and  Inflammation. 28230744

2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker RGD Gender Differences in the Acute Kidney Injury to Chronic Kidney Disease Transition. 28947737

2017
Entrez Id: 506
Gene Symbol: ATP5F1B
ATP5F1B
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker CTD_mouse Urinary ATP Synthase Subunit β Is a Novel Biomarker of Renal Mitochondrial Dysfunction in Acute Kidney Injury. 25666834

2015
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Therapeutic RGD Olmesartan protects against oxidative stress possibly through the Nrf2 signaling pathway and inhibits inflammation in daunorubicin-induced nephrotoxicity in rats. 24291173

2014
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Therapeutic RGD Heme oxygenase 1 modulates thrombomodulin and endothelial protein C receptor levels to attenuate septic kidney injury. 23807243

2013
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker RGD Bilirubin attenuates the renal tubular injury by inhibition of oxidative stress and apoptosis. 23683031

2013
Entrez Id: 26762
Gene Symbol: HAVCR1
HAVCR1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker RGD Bilirubin attenuates the renal tubular injury by inhibition of oxidative stress and apoptosis. 23683031

2013
Entrez Id: 1191
Gene Symbol: CLU
CLU
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker RGD Tissue Kim-1 and urinary clusterin as early indicators of cisplatin-induced acute kidney injury in rats. 22581811

2012
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker RGD Altered regulation of nitric oxide and natriuretic peptide system in cisplatin-induced nephropathy. 22209992

2012
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Therapeutic RGD Prevention of acute kidney injury in a rodent model of cirrhosis following selective gut decontamination is associated with reduced renal TLR4 expression. 22266601

2012
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 ModifyingMutation RGD Cisplatin induces Sirt1 in association with histone deacetylation and increased Werner syndrome protein in the kidney. 21416250

2011
Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Therapeutic RGD N-acetylcysteine attenuates glycerol-induced acute kidney injury by regulating MAPKs and Bcl-2 family proteins. 20037173

2010
Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker RGD Differential expression of plasma proteins in cyclosporine A-induced rat acute nephrotoxicity. 19270397

2009
Entrez Id: 4353
Gene Symbol: MPO
MPO
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker RGD Halofuginone has a beneficial effect on gentamicin-induced acute nephrotoxicity in rats. 19793022

2009
Entrez Id: 2671
Gene Symbol: GFER
GFER
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Therapeutic RGD Expression of augmenter of liver regeneration in rats with gentamicin-induced acute renal failure and its protective effect on kidney. 20030531

2009
Entrez Id: 2671
Gene Symbol: GFER
GFER
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker RGD Expression of augmenter of liver regeneration in rats with gentamicin-induced acute renal failure and its protective effect on kidney. 20030531

2009
Entrez Id: 567
Gene Symbol: B2M
B2M
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker RGD Discrepancy between serum levels of low molecular weight proteins in acute kidney injury model rats with bilateral ureteral obstruction and bilateral nephrectomy. 19536607

2009
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Therapeutic RGD Ciglitazone, a peroxisome proliferator-activated receptor gamma inducer, ameliorates renal preglomerular production and activity of angiotensin II and thromboxane A2 in glycerol-induced acute renal failure. 17494862

2007
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker RGD Control of the epidermal growth factor receptor and its ligands during renal injury. 11340354

2001
Entrez Id: 1839
Gene Symbol: HBEGF
HBEGF
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker RGD Control of the epidermal growth factor receptor and its ligands during renal injury. 11340354

2001
Entrez Id: 7056
Gene Symbol: THBD
THBD
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.300 Therapeutic RGD Soluble thrombomodulin protects ischemic kidneys. 19176699

2009
Entrez Id: 407015
Gene Symbol: MIR26A1
MIR26A1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker CTD_rat A scrutiny of circulating microRNA biomarkers for drug-induced tubular and glomerular injury in rats. 30682439

2019
Entrez Id: 407015
Gene Symbol: MIR26A1
MIR26A1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD A scrutiny of circulating microRNA biomarkers for drug-induced tubular and glomerular injury in rats. 30682439

2019
Entrez Id: 55669
Gene Symbol: MFN1
MFN1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Disrupted Renal Mitochondrial Homeostasis after Liver Transplantation in Rats. 26480480

2015
Entrez Id: 51024
Gene Symbol: FIS1
FIS1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Disrupted Renal Mitochondrial Homeostasis after Liver Transplantation in Rats. 26480480

2015