Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 1337 31
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1254 10
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885 603 4
MBL2 P11226 mannose binding lectin 2 Receptor 2.7E-03 0.390 0.846 563 21
LCN2 P80188 lipocalin 2 Enzyme 1.1E-09 0.405 0.885 497 3
TIMP2 P16035 TIMP metallopeptidase inhibitor 2 Enzyme modulator 0.79 0.425 0.846 404 20
ARTN Q5T4W7 artemin Signaling 0.36 0.480 0.846 248 0
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 245 30
AGRP O00253 agouti related neuropeptide Signaling 7.0E-04 0.488 0.769 233 2
DAG1 Q14118 dystroglycan 1 Receptor 0.98 0.498 0.808 230 15
ELK3 P41970 ETS transcription factor ELK3 Transcription factor 8.4E-02 0.490 0.846 220 2
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808 207 22
ALOX15 P16050 arachidonate 15-lipoxygenase Enzyme 1.1E-23 0.502 0.846 205 5
PSAP P07602 prosaposin 0.99 0.532 0.846 189 15
DEFB4A O15263 defensin beta 4A 1.2E-03 0.507 0.769 177 0
DEFB4B O15263 defensin beta 4B 6.8E-02 0.510 0.769 166 0
LTF P02788 lactotransferrin Enzyme 1.3E-21 0.543 0.846 133 13
CD2AP Q9Y5K6 CD2 associated protein 0.23 0.558 0.731 113 14
KLK4 Q9Y5K2 kallikrein related peptidase 4 Enzyme 4.5E-06 0.559 0.692 110 8
ANLN Q9NQW6 anillin actin binding protein 0.14 0.644 0.500 54 7
MMP20 O60882 matrix metallopeptidase 20 Enzyme 6.1E-14 0.663 0.538 40 9
ELK4 P28324 ETS transcription factor ELK4 Transcription factor 3.4E-03 0.674 0.423 32 0