Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.700 None 0.994 52 0 1992 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.700 None 0.990 39 0 2003 2020
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
solute carrier family 5 member 5 0.499 0.769 2.9E-03
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.400 None 1.000 7 0 1997 2020
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
galectin 3 0.392 0.846 2.3E-05
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.100 None 1.000 7 0 1997 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.400 None 1.000 6 0 2001 2017
Entrez Id: 2335
Gene Symbol: FN1
FN1
fibronectin 1 0.365 0.962 1.4E-03
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.100 None 1.000 5 0 1999 2016
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.400 None 1.000 5 0 1998 2019
Entrez Id: 7424
Gene Symbol: VEGFC
VEGFC
vascular endothelial growth factor C 0.459 0.769 0.50
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.070 None 0.857 5 0 2000 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.400 None 0.953 5 0 1991 2019
Entrez Id: 7015
Gene Symbol: TERT
TERT
telomerase reverse transcriptase 0.374 0.846 0.99
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.400 None 0.939 4 0 1999 2020
Entrez Id: 9232
Gene Symbol: PTTG1
PTTG1
PTTG1 regulator of sister chromatid separation, securin 0.526 0.654 4.2E-04
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.060 None 1.000 4 0 2003 2017
Entrez Id: 7038
Gene Symbol: TG
TG
thyroglobulin 0.480 0.808 2.9E-59
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.100 None 0.927 4 0 1983 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.100 None 1.000 4 0 1995 2019
Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1
NK2 homeobox 1 0.457 0.808 0.36
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.100 None 1.000 3 0 1994 2020
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
cyclin dependent kinase inhibitor 1A 0.403 0.769 1.9E-03
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.260 None 1.000 3 0 1996 2014
Entrez Id: 355
Gene Symbol: FAS
FAS
Fas cell surface death receptor 0.372 0.923 0.81
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.060 None 1.000 3 0 1999 2008
Entrez Id: 3397
Gene Symbol: ID1
ID1
inhibitor of DNA binding 1, HLH protein 0.544 0.692 3.1E-04
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.030 None 1.000 3 0 2003 2005
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
C-X-C motif chemokine receptor 4 0.362 0.923 1.8E-02
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.060 None 1.000 3 0 2003 2016
Entrez Id: 7173
Gene Symbol: TPO
TPO
thyroid peroxidase 0.455 0.846 1.8E-21
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.100 None 1.000 3 0 1994 2020
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.090 None 1.000 3 0 2008 2017
Entrez Id: 7253
Gene Symbol: TSHR
TSHR
thyroid stimulating hormone receptor 0.486 0.808 3.0E-15
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.400 None 0.906 3 0 1991 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.200 None 0.957 3 0 1997 2019
Entrez Id: 7849
Gene Symbol: PAX8
PAX8
paired box 8 0.477 0.731 1.00
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.100 None 0.970 3 0 1994 2019
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
HNF1 homeobox B 0.473 0.808 1.00
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.030 None 1.000 3 0 2005 2008
Entrez Id: 5168
Gene Symbol: ENPP2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2 0.582 0.769 2.8E-03
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.320 None 1.000 2 0 2004 2015