| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.900 | strong | 0.915 | 1 | 0 | 1998 | 2020 | ||||||||
|
glutathione-disulfide reductase | 0.494 | 0.846 | 1.3E-06 |
|
disease | 0.240 | None | 1.000 | 1 | 0 | 1998 | 2018 | ||||||||
|
caspase 3 | 0.351 | 0.923 | 0.10 |
|
disease | 0.600 | None | 0.980 | 3 | 0 | 1999 | 2020 | ||||||||
|
advanced glycosylation end-product specific receptor | 0.420 | 0.885 | 6.4E-16 |
|
disease | 0.300 | None | 0.978 | 1 | 0 | 1999 | 2019 | ||||||||
|
beta-secretase 1 | 0.559 | 0.769 | 0.88 |
|
disease | 0.600 | None | 0.985 | 1 | 0 | 1999 | 2020 | ||||||||
|
insulin degrading enzyme | 0.604 | 0.577 | 6.6E-03 |
|
disease | 0.600 | None | 0.955 | 4 | 0 | 2000 | 2019 | ||||||||
|
glycogen synthase kinase 3 beta | 0.430 | 0.846 | 0.96 |
|
disease | 0.700 | None | 0.982 | 3 | 0 | 2000 | 2020 | ||||||||
|
ADAM metallopeptidase domain 10 | 0.489 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.986 | 2 | 0 | 2000 | 2019 | ||||||||
|
ADAM metallopeptidase domain 17 | 0.453 | 0.808 | 1.00 |
|
disease | 0.260 | None | 1.000 | 1 | 0 | 2000 | 2018 | ||||||||
|
caspase 9 | 0.458 | 0.808 | 7.4E-06 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2000 | 2018 | ||||||||
|
nitric oxide synthase 2 | 0.364 | 0.923 | 4.0E-15 |
|
disease | 0.300 | None | 0.923 | 1 | 0 | 2000 | 2019 | ||||||||
|
cyclin dependent kinase 5 | 0.495 | 0.846 | 0.14 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2000 | 2020 | ||||||||
|
mitogen-activated protein kinase 14 | 0.379 | 0.923 | 0.37 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2000 | 2020 | ||||||||
|
neuropeptide Y | 0.447 | 0.846 | 0.14 |
|
disease | 0.600 | None | 0.833 | 1 | 0 | 2000 | 2018 | ||||||||
|
membrane metalloendopeptidase | 0.407 | 0.808 | 1.5E-18 |
|
disease | 0.300 | None | 0.955 | 1 | 0 | 2001 | 2020 | ||||||||
|
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.488 | 0.769 | 0.74 |
|
disease | 0.300 | None | 0.979 | 0 | 0 | 2001 | 2019 | ||||||||
|
INS-IGF2 readthrough | 0.633 | 0.500 | 5.6E-02 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2002 | 2007 | ||||||||
|
insulin receptor | 0.432 | 0.846 | 3.6E-05 |
|
disease | 0.600 | None | 1.000 | 1 | 0 | 2002 | 2020 | ||||||||
|
heat shock protein family D (Hsp60) member 1 | 0.432 | 0.808 | 0.99 |
|
disease | 0.240 | None | 1.000 | 1 | 0 | 2002 | 2018 | ||||||||
|
insulin like growth factor 2 | 0.390 | 0.885 | 4.4E-02 |
|
disease | 0.570 | None | 1.000 | 1 | 0 | 2002 | 2019 | ||||||||
|
plasminogen activator, urokinase | 0.425 | 0.923 | 2.3E-06 |
|
disease | 0.680 | None | 1.000 | 0 | 0 | 2002 | 2013 | ||||||||
|
dynamin 1 | 0.595 | 0.692 | 1.00 |
|
disease | 0.260 | None | 1.000 | 1 | 0 | 2003 | 2020 | ||||||||
|
ATP synthase F1 subunit alpha | 0.604 | 0.731 | 1.00 |
|
disease | 0.540 | None | 1.000 | 1 | 0 | 2003 | 2017 | ||||||||
|
BCL2 like 2 | 0.599 | 0.615 | 0.47 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2004 | 2010 | ||||||||
|
C-C motif chemokine receptor 5 (gene/pseudogene) | 0.398 | 0.885 | 4.3E-10 |
|
disease | 0.240 | None | 0.800 | 1 | 0 | 2004 | 2019 |